Plexaderm works best on its own. For maximum results we recommend avoiding the use of moisturizers on areas where you have applied Plexaderm for the duration of its active cycle, on average 6 to 8 hours.

We understand that everyone’s skin needs are different. Should your skin require a moisturizer along with Plexaderm, it is recommended that it be a water-based moisturizer as oil-based products may deactivate the Plexaderm effects. For best results, apply your water-based moisturizer first and allow 10 to 20 minutes for full absorption before applying Plexaderm.